Search results for "Brachiocephalic vein"

showing 6 items of 6 documents

Possible Pathomechanisms Responsible for Injury to the Central Nervous System in the Settings of Chronic Cerebrospinal Venous Insufficiency

2012

The discovery of stenoses in the azygous and internal jugular veins, the so-called chronic cerebrospinal venous insufficiency that accompanies multiple sclerosis, has enabled the reinterpretation of knowledge about this neurologic dis- ease. Pathologic venous outflow from the central nervous system appears to lead to two main problems. Firstly, it disas- sembles the blood-brain barrier and may allow the penetration of nervous parenchyma by glutamate and leukocytes. Sec- ondly, it may result in significant hypoperfusion of the brain and spinal cord. These two overlapping pathologies are likely to trigger plaques through caspase-1-driven pyroptosis of oligodendrocytes and to evoke neurodegene…

Central Nervous SystemPathologymedicine.medical_specialtyCentral nervous systemExcitotoxicityglutamatemultiple sclerosismedicine.disease_causeAxonal injuryCentral Nervous System Diseasescaspase 1venous insufficiencymedicineHumansBrachiocephalic Veinsjugular veinsPharmacologybusiness.industryMultiple sclerosisazygous veinNeurodegenerationPyroptosisGlutamate receptorGeneral Medicineblood-brain barriermedicine.diseaseSpinal cordChronic cerebrospinal venous insufficiencymedicine.anatomical_structureSpinal CordbusinessReviews on Recent Clinical Trials
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Is It Possible to Create a “Mechanical” Arteriovenous Fistula in Hemodialysis Patients?

2010

Manual suturing still remains the best technique for the creation of vascular anastomoses on uremic patients with excellent results, despite being time consuming, difficult to perform with small vessels, and associated with a significant learning curve. We created a full mechanical arteriovenous fistula on a 65-year-old uremic patient with a new device already used in cardiac bypass surgery. The fistula was created automatically and rapidly, without the need for temporary occlusion of the artery, reducing the risk of blood clotting. We believe that mechanical devices may be useful to produce precise and fast anastomoses requiring minimal training for the surgeon.

Malemedicine.medical_specialtymedicine.medical_treatmentFistulaBiomedical EngineeringMedicine (miscellaneous)Arteriovenous fistulaBioengineeringAnastomosisBiomaterialsArteriovenous Shunt SurgicalRenal DialysisHumansMedicineDialysisAgedBrachiocephalic VeinsUremiaArteriovenous fistulaDialysisSutureless mechanical anastomosisUremiabusiness.industrySuture TechniquesEquipment DesignGeneral Medicinemedicine.diseaseUremiaSurgerySettore MED/18 - Chirurgia Generalemedicine.anatomical_structureBypass surgeryRadial ArteryHemodialysisbusinessArteryArtificial Organs
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Prevalence of extracranial venous abnormalities: results from a sample of 586 multiple sclerosis patients

2011

The aim of this study was to assess the prevalence of chronic cerebrospinal venous insufficiency in an unselected cohort of multiple sclerosis (MS) patients. A total of 586 patients with clinically defined MS underwent catheter venography of the internal jugular veins, brachiocephalic veins and azygos vein. The following findings were regarded as pathologic: no outflow, slowed outflow, reversal of flow direction, prestenotic dilation accompanied by impaired outflow, outflow through collaterals, intraluminal structures obstructing the vein, hypoplasia, agenesia or significant narrowing of the vein. Venous abnormalities were found in 563 patients (96.1%). Lesions in one vein were found in 43.…

azygos veinmultiple sclerosisvascular malformationsbrachiocephalic veinsjugular veinsFunctional Neurology
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Numerical modeling of blood flow in the internal jugular vein with the use of computational fluid mechanics software.

2021

ObjectivesTo determine the site and nature of altered hemodynamics in pathological internal jugular veins.MethodWith the use of computational fluid mechanics software we simulated blood flow in 3 D models of the internal jugular veins that exhibited different morphologies, including nozzle-like strictures in their upper parts and valves in the lower parts.ResultsIn a majority of models with nozzle-like strictures, especially those positioned asymmetrically, abnormal flow pattern was revealed, with significant flow separation and regions with reversed flow. Abnormal valves had no significant impact on flow in a case of already altered flow evoked by stricture in upper part of the vein.Conclu…

business.industryHemodynamicsNumerical modelingHemodynamicsFluid mechanicsGeneral MedicineBlood flowConstriction Pathologic030204 cardiovascular system & hematology03 medical and health sciencesFlow separation0302 clinical medicineSoftwareRegional Blood FlowMedicineHumansComputational fluid mechanics; flow separation; internal jugular vein; minor losses; numerical modelingJugular VeinsCardiology and Cardiovascular MedicinebusinessInternal jugular vein030217 neurology & neurosurgerySoftwareBiomedical engineeringBrachiocephalic VeinsPhlebology
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Obstructive Malformations of the Internal Jugular Vein

2021

Obstructive malformations of the internal jugular veins represent a relatively new clinical problem, which as of yet has not been fully understood. In normal subjects, the internal jugular vein is valveless, except for a single valve, situated just above the junction of this vein with the brachiocephalic vein. Usually, normal jugular valves exhibit a two-leaflet structure. Stenotic lesions of these veins were described for the first time in 2009 in a group of multiple sclerosis patients. The most common obstructive malformation of the internal jugular vein is a stenotic valve. There are several morphological types of such aberrant valves, comprising annular stenoses, valves with fused, reve…

business.industryMultiple sclerosisCentral nervous systemAnatomymedicine.diseaseChronic cerebrospinal venous insufficiencymedicine.anatomical_structurecardiovascular systemMedicineGlymphatic systemClinical significancecardiovascular diseasesbusinessVeinInternal jugular veinBrachiocephalic vein
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The use of a new kind of low profile retractor for arteriovenous fistula procedure simplifies and speeds up the intervention

2009

Purpose The aim of this study was to demonstrate the effectiveness of a new kind of disposable surgical retractor in arteriovenous fistula (AVF) procedures in order to achieve an easier, faster and safer surgical intervention. Methods Between January and June 2008, 22 AVF procedures were performed using the 3PAWS ReeTrakttrade; (Insightra Inc. - Irvine, Ca., USA) a self-retaining, low profile retractor. An equivalent patient sample, in which an AVF was performed using conventional retraction devices, was considered for comparison of the intra- and post-operative results. Results In all of the 22 AVF procedures performed, the ReeTrakt™ system has simplified the performance of the surgical te…

medicine.medical_specialtyTime Factorsmedicine.medical_treatment030232 urology & nephrologyArteriovenous fistulaarterioveunous fistula retractors030204 cardiovascular system & hematology03 medical and health sciencesArteriovenous Shunt Surgical0302 clinical medicineOperating timeHumansMedicinePatient groupDisposable EquipmentReduction (orthopedic surgery)Brachiocephalic VeinsRetrospective StudiesSurgical teamSurgical instrumentationSurgical Fixation Devicebusiness.industryEquipment DesignSurgical Instrumentsmedicine.diseasearteriovenous fistulaReeTrakt systemSurgeryRetractorForearmSettore MED/18 - Chirurgia GeneraleTreatment OutcomeNephrologyRadial ArterySurgerybusiness
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